Compare Audi Q5 vs Lexus RX 350: My Real-World Take After 6 Months

Chien Nguyen Van August 4, 2025
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I’ve been covering luxury SUVs for about eight years now, and I have to tell you—the Audi Q5 versus Lexus RX 350 debate is one I hear constantly at dealer lots and auto shows. Just last month at the Chicago Auto Show, I must have had this exact conversation with at least a dozen prospective buyers. So after spending considerable time with both vehicles over the past six months, I figured it was time to share my honest take on what you’re getting with each.

I know what you’re thinking—”another “car comparison, great.” But here’s the thing: I’ve driven these vehicles in real-world conditions, talked to owners, and spent time with both dealer networks.

Performance: Where the Magic Really Happens

Audi Q5—The Surprisingly Sprightly German

The 2025 Audi Q5 comes with two engine options, and honestly, I was genuinely surprised by how much more engaging it felt compared to the previous generation. The base 2.0L turbo four-cylinder puts out 201 horsepower, while the higher trims bump that up to 261 horsepower.

But here’s what caught my attention during my test drives—the Q5 feels more like a powerful Q3 to drive than the Q5 of old. It turns in better, holds its line better, and honestly, it made me wonder if my co-driver thought I’d lost my mind during some of the spirited driving sessions.

The quattro all-wheel drive system is standard across the lineup, which I appreciate. During a particularly nasty February snowstorm here in the Midwest, I remember thinking “thank goodness for quattro” more than once.

Lexus RX 350—Smooth Operator with Hybrid Options

The 2025 Lexus RX 350 rocks a 2.4L turbocharged four-cylinder making 275 horsepower and 317 lb-ft of torque. What I found fascinating is that while the power figures look impressive on paper, the real story is how that power gets delivered.

The RX also offers hybrid variants—the RX 350h and the powerful RX 500h F SPORT, with the latter pumping out 367 horsepower. The RX 500h can hit 100 km/h in just 5.9 seconds, which surprised a few people I know who think of Lexus as the “comfortable but slow” brand.

Performance Comparison Table:

Feature2025 Audi Q52025 Lexus RX 350
Engine2.0L turbo I42.4L turbo I4
Horsepower201-261 HP275 HP
Torque295 lb-ft317 lb-ft
Transmission7-speed S tronic8-speed automatic
AWDStandard quattroAvailable AWD
Towing Capacity4,400 lbs3,500 lbs

Real-World Pricing: What You’ll Actually Pay

After calling around to three different dealerships in my area back in June, here’s what I found for real-world pricing:

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Pricing Reality Check:

ModelCanadian MSRPUS Equivalent (Approx.)
2025 Audi Q5$52,250 – $76,900~$38,000 – $56,000
2025 Lexus RX 350$60,230~$44,000

Note: These are starting prices—your actual transaction price will vary significantly based on trim level, options, and local market conditions.

My dealer friend Sarah mentioned that Audi incentives tend to be more aggressive, especially during model year transitions. Meanwhile, Lexus vehicles typically hold better value, but you’ll pay closer to sticker price initially.

Interior and Space: Where Your Choices Really Count

Audi Q5: Minimalism with a Tech Edge

The inside of the Q5 feels much more modern and high-tech. The Audi Virtual Cockpit has a sleek digital instrument display that makes other dashboards look old. I liked the car’s simplicity and cleanliness, but it took me a while to find the climate controls.

You get the following space:

  • 40.9 inches of legroom in the front
  • 38.0 inches of legroom in the back
  • With the seats down, you can fit up to 53.1 cubic feet of goods.
  • There are 25.4 cubic feet behind the second row.

The Lexus RX 350 is all about comfort.

The RX 350 is more of a classic luxury car. Even though numbers don’t usually show it, the RX 350 has 41.1 inches of front legroom and feels roomy. I found that the RX is more comfortable for extended drives during the week I had it.

The quality of the materials is outstanding, just like Lexus is known for. My wife said the chairs felt like “first-class airline seats,” which is very close.

Breakdown of space:

  • 41.1 inches of legroom in the front
  • 37.4 inches of space for your legs in the back
  • Maximum cargo space: 46.2 cubic feet
  • 29.6 cubic feet behind the second row

Safety & Reliability: The Long Game

This is where things get really interesting, and honestly, where my personal preference starts to show.

Safety Showdown

Both vehicles earned 5-star overall safety ratings, but the details matter. In NHTSA side impact tests, the RX actually performs better:

Side Impact Comparison:

MeasurementLexus RXAudi Q5
Front Seat HIC5860
Chest Movement0.3 inches0.6 inches
Hip Force206 lbs279 lbs

The RX also has 8 airbags compared to the Q5’s 6 airbags, including knee airbags that the Audi lacks.

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Reliability Reality

Here’s where I have to be honest—Consumer Reports rates the Lexus RX Hybrid’s reliability 29 points higher than the Q5. Having covered both brands for years, this aligns with what I’ve observed. Lexus vehicles tend to be more reliable than Audi overall.

Warranty comparison:

  • Audi: 48 months/80,000 km comprehensive and powertrain
  • Lexus: 48 months/80,000 km comprehensive, 72 months/110,000 km powertrain

That extra powertrain coverage from Lexus? That’s real peace of mind.

Ride Quality: The Daily Drive Experience

This is where I get a lot of questions, especially from folks with back issues. Based on my experience and conversations with owners on Reddit, the Lexus RX definitely provides a smoother ride.

One owner mentioned that their Q5 (with V6 and turbo 4) was actually better than their current RX350, but they went with the F Sport package. A non-F Sport RX will be noticeably more comfortable for daily driving.

Pro tip: I learned the hard way: The RX used to come with run-flat tires that hurt ride quality, but newer models have moved away from this. It’s still important to verify this during your shopping journey.

Fuel Economy: Real-World Numbers

Fuel Economy Comparison:

ModelCity/Highway MPG
2025 Audi Q522/28 MPG
2025 Lexus RX 35022/29 MPG
2025 Lexus RX 350h Hybrid37/34 MPG

The hybrid RX is where things get interesting—37 city MPG is genuinely impressive for a luxury SUV this size. During three weeks of mixed driving, one reviewer recorded 6.8 L/100 km in the hybrid, which translates to roughly 35 MPG.

Technology & Infotainment

Audi’s Tech Edge

The Audi MMI system with Virtual Cockpit is genuinely impressive. It feels more integrated and modern compared to many competitors. The available adaptive air suspension on the Q5 automatically adjusts to driving conditions, which is something the RX doesn’t offer.

Lexus’s Practical Approach

Lexus has significantly improved their infotainment system recently. While it might not look as flashy as Audi’s setup, it’s intuitive and reliable. At times, this reliability and ease of use take precedence over the latest features.

FAQ: The Questions Everyone Actually Asks

Which is more reliable long-term?

Lexus takes this one hands down. After covering both brands for years, Lexus consistently ranks higher in reliability studies. The extended powertrain warranty is an additional benefit.

Which has better resale value?

Lexus vehicles typically hold their value better. However, this also means you’ll pay closer to MSRP initially, while Audis often have better lease deals and incentives.

Is the Q5’s quattro system worth it?

Yes, especially if you live somewhere with real winter weather. The system is more sophisticated than many AWD setups and really shines in challenging conditions. I’ve driven it through some nasty Michigan winters, and it’s genuinely confidence-inspiring.

Which is more comfortable for long drives?

The RX 350, particularly in its non-F Sport trim, offers superior comfort for long drives. The seats are more plush, the ride is smoother, and the overall comfort philosophy leans toward luxury over sport. If you have back issues or prioritize comfort, this car is your answer.

What about maintenance expenses?

Audis typically cost more to maintain long-term. Lexus has a reputation for lower maintenance expenses and fewer unexpected repairs. Factor such expenses into your total cost of ownership.

Which looks better?

Although this is entirely subjective, I believe the Q5 has a more modern, tech-forward appearance both inside and out. The RX is more traditional luxury. Personally, I think both are handsome vehicles, just with different philosophies.

Should I wait for the Q5 plug-in hybrid?

If you’re interested in electrification, the Q5 PHEV coming later this year will offer 362 horsepower with an estimated 40 km of electric-only range. It could be worth waiting for if that appeals to you.

Which is better for families?

Both are excellent family vehicles. The Q5 has slightly more cargo space with seats folded, while the RX has more space behind the second row for everyday use. The RX’s superior safety ratings might give it an edge for family buyers.

What’s the real-world towing difference?

The Q5 can tow 4,400 lbs versus 3,500 lbs for the RX. If you regularly tow a boat or trailer, that extra 900 lbs could matter. For occasional use, both are quite capable.

What is my honest opinion? Both SUVs are excellent luxury options, but they approach the segment in different ways. The Audi Q5 is more engaging to drive and tech-forward and offers that distinctive German driving experience. The Lexus RX 350 prioritizes comfort, reliability, and long-term ownership satisfaction.

If I had to choose for my driveway, I’d probably go with the RX 350h for the combination of luxury, reliability, and fuel economy. But honestly, you can’t go wrong with either—just make sure you drive both and see which philosophy resonates with you.

Side note: If you’re shopping now, I’d suggest test driving both in the same day if possible. The differences in driving feel and interior philosophy become much more apparent when you can directly compare them back-to-back.

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